Hypoxia and proangiogenic proteins in human ameloblastoma
نویسندگان
چکیده
منابع مشابه
Midkine acts as proangiogenic cytokine in hypoxia-induced angiogenesis.
The cytokine midkine (MK) promotes tumor growth mainly by inducing angiogenesis. Here, we identified the source of MK in the vascular system under hypoxic conditions and demonstrated the relevance of MK during ischemia of normal tissue. Hypoxia increased MK protein expression in human polymorphonuclear neutrophils (PMN), monocytes, and human umbilical vein endothelial cells (HUVEC) compared wit...
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Aims: The aim of the current study was to detect and compare Human papillomavirus (HPV) in dentigerous cyst and ameloblastoma. Materials and methods: The study included 32 samples, which distributed into dentigerous cysts (n=16) and ameloblastomas (n=16). Conventional PCR assay using SPF1/2 consensus primers and immunohistochemical analysis were performed for the detection of HPV‒DNA and HPV‒L1...
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As a highly conserved signaling pathway, Wnt/β-catenin signal transduction pathway plays an important role in many processes. Either in the occurrence or development of tumor, activation of this pathway takes an important place. APC inhibits Wnt/β-catenin pathway to regulate cell proliferation and differentiation. This study aimed to investigate the function of cancer suppressor gene. PCR ampli...
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Various cell proliferation markers are used as diagnostic and prognostic tools in oral lesions. Simultaneous evaluation of these markers can increase the precision of estimation of the proliferative status of different tissues. In this study we investigated the expression of PCNA and Ki-67 as markers of cell proliferation in 15 paraffin embedded samples of each dental follicle, dentigerous cy...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-74693-7